Figure 2. Visual Analog Scale (VAS) scores of physical fatigue-related outcomes during use of the investigational product or placebo. Treatment differences were analyzed using linear mixed-effects models for repeated measures, with treatment, intervention period, assessment time, treatment sequence, age, and the treatment-by-time interaction included as fixed effects, and participant included as a random intercept to account for within-participant correlation. Data are presented as individual observations, mean ± standard deviation (S.D.) (diamond and error bars), and estimated least-squares (LS) mean with 95% confidence interval (horizontal line and box). None of the investigational product versus placebo contrasts remained significant after Benjamini–Hochberg false discovery rate (FDR) adjustment : Effects of a Multi-Ingredient Dietary Supplement on Sexual Well-Being in Healthy Men: A Retrospective Analysis of a Randomized, Double-Blind, Placebo-Controlled Crossover Product-Monitoring Study : Science and Education Publishing

Figure 2. Visual Analog Scale (VAS) scores of physical fatigue-related outcomes during use of the investigational product or placebo. Treatment differences were analyzed using linear mixed-effects models for repeated measures, with treatment, intervention period, assessment time, treatment sequence, age, and the treatment-by-time interaction included as fixed effects, and participant included as a random intercept to account for within-participant correlation. Data are presented as individual observations, mean ± standard deviation (S.D.) (diamond and error bars), and estimated least-squares (LS) mean with 95% confidence interval (horizontal line and box). None of the investigational product versus placebo contrasts remained significant after Benjamini–Hochberg false discovery rate (FDR) adjustment

Journal of Food and Nutrition Research. 2026, 14(9), 185-194 doi:10.12691/jfnr-14-9-1