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From
Dual Epigenetic Impacts of Temozolomide on the Sensitivity of ER-positive and ER-negative Breast Cancer and Glioma Cells
Viacheslav S, Jorge S., Perez C., Prajapati J., Diaz A.J., Wang T.
American Journal of Medicine Studies
.
2026
, 11(1), 8-15 doi:10.12691/ajms-11-1-2
Table 1. Definition of Wilcoxon test statistic parameters
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Table 2. Statistical significance of U87 glioma viability data, n=9
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Table 3. Statistical significance of MDA-MB-231 TNBC viability data, n=9
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Table 4. Statistical significance of MCF-7 (ER-positive breast cancer) viability data, n=9
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Table 5. MCF-7 viability and inhibition% data following TMZ treatment (48 hr exposure, n=9)
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Table 6. 4PL model optimization for MCF-7 IC50 determination
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Table 7. MDA-MB-231 TNBC viability and inhibition% data following TMZ treatment (48 hr exposure, n=9)
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Table 8. 4PL model optimization for MDA-MB-231 breast cancer cells IC50 determination
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Table 9. Glioma U87 cell viability and inhibition% data following TMZ treatment (48 hr exposure, n=9)
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Table 10. 4PL model optimization for glioma U87 cells IC50 determination
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Table 11. Summary of IC₅₀ values and interpretation across the three cell lines
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Table 12. Principal DNA repair mechanisms counteracting TMZ-induced DNA methylation
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