Figure 4 Comparison of TMZ sensitivity in ER-positive MCF-7, ER-negative MDA-MB-231 breast cancer, and U87 glioma cancer cells. MMR-dominant DNA damage and other nucleophilic target damage (MCF-7, MDA-MB-231) favor cell death, whereas MGMT-dominant repair and other damage repair (U87) favor cell survival

From

Dual Epigenetic Impacts of Temozolomide on the Sensitivity of ER-positive and ER-negative Breast Cancer and Glioma Cells

Viacheslav S, Jorge S., Perez C., Prajapati J., Diaz A.J., Wang T.

American Journal of Medicine Studies. 2026, 11(1), 8-15 doi:10.12691/ajms-11-1-2