Figure 5. Effects of Bangle extract (Ba) on Sirius-red-stained fibrotic areas in the gastrocnemius muscle (GM) of high-fat diet (HFD)-fed SAMP8 mice. (A) Rcon (SAMR1 control), (B) Con (SAMP8 control), (C) HFD + 0% Ba, and (D) HFD + 2% Ba groups. Sirius-red-staining was carried out (Original magnification 200×, Scale bar: 50 μm). Percentage area of fibrosis per total cross-sectional area (E). Values are presented as mean ± SEM (n = 5–8). ^aP < 0.05 compared with Rcon group. ^bP < 0.05 compared with Con group. ^cP < 0.05 compared with HFD+0%Ba group

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Bangle (Zingiber purpureum) Extract Attenuates Insulin Resistance and Inflammation in the Skeletal Muscle of High Fat Diet-fed Young SAMP8 Mice

Shin Sato, Nagomi Takahashi, Yuuka Mukai

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