Figure 2. PU protects against cytotoxicity via SIRT1 activation in HepG2 cells: (A) Western blot was used to analyze the expression of SIRT1 in HepG2 cells. (B) HepG2 cells were transfected with siRNA against SIRT1 and then were treated with PU/PA, and the expression levels of cleaved-PARP and SIRT1 were analyzed by western blotting

From

Punicalagin Inhibits Palmitate Acid-induced Lipoapoptosis through Inhibition of ER Stress, and Activation of SIRT1/Autophagy in HepG2 Cells

Han Zhang, Hao Wu, Shutao Yin, Hongbo Hu, Chong Zhao

Journal of Food and Nutrition Research. 2020, 8(9), 536-542 doi:10.12691/jfnr-8-9-10