Figure 7. Fucoxanthin-rich brown algae extract decreases oxidative stress and pro-inflammatory cytokine expression in CACC mice. Mice were grouped and fed with FX-BAE at dosages of 0.5, 1, or 2.5 g/kg every two days. (A) Total NO and (B) MDA production of colonic tissue was decreased in the 1 and 2.5 mg/kg FX-BAE treatment groups (p < 0.05; Figure 5A-B). (C) FXBAE decreased the release of NO, and lessened the secretion of (D) TNF-α and (E) IL-6 in colonic tissue. Curcumin (75 mg/kg every 2 days) was used as a positive control. Data are reported as means ±SD (n = 10 mice/group). Different letters indicate significant differences, with p < 0.05

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Fucoxanthin-Rich Brown Algae Extract Decreases Inflammation and Attenuates Colitis-associated Colon Cancer in Mice

Zwe-Ling Kong, Ning-Jo Kao, Jia-Yuan Hu, Chien-Sheng Wu

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