Figure 6. Incidence of colonic neoplasm change in CACC mouse model after treatment with fucoxanthin-rich brown algae extract. CACC mice were grouped and fed with FX-BAE at dosages of 0, 0.5, 1, or 2.5 g/kg every 2 days. (A) There was a significant reduction of DAI score of disease animals that received FX-BAE at 7 weeks. The data shows 2.5 g/kg/day dosage of FX-BAE produced greater efficacy than CACC mice fed with 75 mg/kg curcumin. Data are reported as means ±SD (n = 10 mice/group). (B) The incidence of AOM and DSS-induced colonic neoplasm was reduced by nearly 50% after treatment with FX-BAE, similar to the effects of curcumin treatment. Data are reported as means ±SD (n = 10 mice/group). Different letters indicate significantly differences, with p < 0.05 : Fucoxanthin-Rich Brown Algae Extract Decreases Inflammation and Attenuates Colitis-associated Colon Cancer in Mice : Science and Education Publishing

Figure 6. Incidence of colonic neoplasm change in CACC mouse model after treatment with fucoxanthin-rich brown algae extract. CACC mice were grouped and fed with FX-BAE at dosages of 0, 0.5, 1, or 2.5 g/kg every 2 days. (A) There was a significant reduction of DAI score of disease animals that received FX-BAE at 7 weeks. The data shows 2.5 g/kg/day dosage of FX-BAE produced greater efficacy than CACC mice fed with 75 mg/kg curcumin. Data are reported as means ±SD (n = 10 mice/group). (B) The incidence of AOM and DSS-induced colonic neoplasm was reduced by nearly 50% after treatment with FX-BAE, similar to the effects of curcumin treatment. Data are reported as means ±SD (n = 10 mice/group). Different letters indicate significantly differences, with p < 0.05

Journal of Food and Nutrition Research. 2016, 4(3), 137-147 doi:10.12691/jfnr-4-3-2