Figure 8. Hematoxylin and Eosin (H&E) stained liver section showing granulomas (red arrows) with congestion of blood vessels (brown arrows) necrosis (black arrows) and hyaline deposits (white arrows). A group of BALB/c mice infected with L. donovani and or P. berghei parasites before histological analysis of the spleen was carried out at the end of the experimental period. A- L. donovani- P. berghei co-infected group; B- L. donovani only infected mice group; C- P. berghei only and D- naïve group). Viewed under a light microscope at X100 magnification

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Concomitant Infection with Leishmania donovani and Plasmodium berghei Causes Pro-inflammatory Polarization Resulting in Malaria Exacerbation in BALB/c Mice

Rebeccah. M. Ayako, Joshua. M. Mutiso, John. C. Macharia, David Langoi, Lucy Ochola

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