Figure 7. Hematoxylin and Eosin (H&E) stained of spleen section showing structural changes in the white (black arrow), red pulps (white arrow) with disorganization of granulomas (red arrows) and yellow arrow demarcating hemozoin. A- L. donovani- P. berghei co-infected group; B- L. donovani only infected mice group; C- P. berghei only and D- naïve group). Viewed under a light microscope at X100 with smaller boxes showing a closer view of granulomas formation (X400 magnification)

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Concomitant Infection with Leishmania donovani and Plasmodium berghei Causes Pro-inflammatory Polarization Resulting in Malaria Exacerbation in BALB/c Mice

Rebeccah. M. Ayako, Joshua. M. Mutiso, John. C. Macharia, David Langoi, Lucy Ochola

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