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From
Lipophilicity and QSAR Study of a Series of Makaluvamines by the Method of the Density Functional Theory: B3LYP/6-311++G(d,p)
Sékou DIOMANDÉ, Soleymane KONÉ
Journal of Materials Physics and Chemistry
.
2019
, 7(1), 20-28 doi:10.12691/jmpc-7-1-3
Figure 1
.
Structures of the studied Makaluvamines (NB: Neutral forms are noted by the refcode X, methylated forms by X
met
)
Full size figure and legend
Figure 2
.
Coefficients defining the contributions of the four descriptors to anticancer activity in model 1
Full size figure and legend
Figure 3
.
Mean regression of experimental anticancer activity in relation with theoretical anticancer activity for all molecules of the training set and the validation set of model
1
Full size figure and legend
Figure 4
.
Coefficients attributed to the different descriptors of models 2, 3 and 4
Full size figure and legend
Figure 5
.
Mean regression of experimental anticancer activity in relation with theoretical anticancer activity for all molecules in the training set and the validation set of three models 2, 3 and 4
Full size figure and legend
Figure 6
.
Structures of Makaluvamines without experimental FC
50
values
Full size figure and legend