Figure 4. Effect of bromelain on the expression of inflammatory genes (Cox-2, TNFα, and iNOS) in LPS-stimulated RAW 264.7 macrophage cells. The cells were treated for 24 h with the indicated concentrations of bromelain before treatment with LPS (1 μg/mL). RT-PCR analysis of cDNA was performed using primers specific for Cox-2, TNFα, and iNOS, with β-actin used for normalization. The PCR bands are representative of experiments and the densitometric graphs (%) show the Cox-2, TNFα, and iNOS ratios relative to the LPS-treated cells, which was set at 100%

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Medicinal Effects of Bromelain (Ananas comosus) Targeting Oral Environment as an Anti-oxidant and Anti-inflammatory Agent

Jung-Ha Lee, Jae-Bong Lee, Jin-Tae Lee, Hae-Ryoun Park, Jin-Bom Kim

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