Figure 5. In vivo induction of cytokines by PTE10 in mouse primary splenocytes. Oral administration of PTE10 enhanced secretion of cytokines in mouse primary splenocytes (A) Expression of IL-1β in primary splenocytes fed PTE10 (500 and 1000 mg/kg body weight). (B) Expression of IL-2 in splenocytes fed PTE10 (500 and 1000 mg/kg body weight). (C) Expression of IL-4 in splenocytes fed PTE10 (500 and 1000 mg/kg body weight). (D) Expression of IFN-γ in splenocytes fed PTE10 (500 and 1000 mg/kg body weight). (E) Expression of iNOS in splenocytes fed PTE10 (500 and 1000 mg/kg body weight). *P < 0.05 compared to control : Porphyra tenera Extracts Have Immune Stimulation Activity via Increasing Cytokines in Mouse Primary Splenocytes and RAW264.7 Macrophages : Science and Education Publishing

Figure 5. In vivo induction of cytokines by PTE10 in mouse primary splenocytes. Oral administration of PTE10 enhanced secretion of cytokines in mouse primary splenocytes (A) Expression of IL-1β in primary splenocytes fed PTE10 (500 and 1000 mg/kg body weight). (B) Expression of IL-2 in splenocytes fed PTE10 (500 and 1000 mg/kg body weight). (C) Expression of IL-4 in splenocytes fed PTE10 (500 and 1000 mg/kg body weight). (D) Expression of IFN-γ in splenocytes fed PTE10 (500 and 1000 mg/kg body weight). (E) Expression of iNOS in splenocytes fed PTE10 (500 and 1000 mg/kg body weight). *P < 0.05 compared to control

Journal of Food and Nutrition Research. 2016, 4(9), 558-565 doi:10.12691/jfnr-4-9-1