Figure 5. Transmission electron micrographs of HUVECs treated with vehicle (A) or 3 μM (B–E) of TS for 24 h. Control cells treated with vehicle exhibited a normal undifferentiated phenotype, showing absence of apoptotic bodies and nuclear condensation, whereas in the TS-treated cells, various kinds of autophagic vesicles (white arrowheads in B) are observed within the cytoplasm. These vesicles include the typical autophagosomes (Au in C), early autolysosomes (D) in which lysosomes (Ly) are still present, and late autolysosomes (E) with degraded amorphous substances. Scale bars represent 5 μm in A and B and 0.5 μm in C–E

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In vitro Anti-angiogenic Effects of Tea Saponin and Tea Aglucone on Human Umbilical Vein Endothelial Cells

Xiaohong Li, Baozhan Huang, Fan Fei, Hai Niu, Wen Huang

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