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From

Effects of High Hydrostatic Pressure Extract of Korean Fresh Ginseng on Hepatic Lipid Accumulation and AMPK Activation in HepG2 Cells

Mak-Soon Lee, Yoonjin Shin, Sunyoon Jung, Chong-Tai Kim, In-Hwan Kim, Yangha Kim

Journal of Food and Nutrition Research. 2015, 3(1), 40-45 doi:10.12691/jfnr-3-1-7
  • Figure 1. Effect of HEG on cell viability in HepG2 cells. Data are presented as mean ± SEM (n = 3) of experiments performed in triplicate. * P < 0.05. HEG, high hydrostatic pressure extract of ginseng
  • Figure 2. (Color online) Effect of HEG on apoptosis in HepG2 cells. Scale bar = 100μm. HEG, high hydrostatic pressure extract of ginseng
  • Figure 3. Effect of HEG on intracellular triglyceride (A) and cholesterol (B) content in HepG2 cells. Data are presented as mean ± SEM (n = 3) of experiments performed in triplicate. * P < 0.05. HEG, high hydrostatic pressure extract of ginseng
  • Figure 4. Effect of HEG on FAS (A) and HMGCR (B) expression in HepG2 cells. Data are presented as mean ± SEM (n = 3) of experiments performed in triplicate. *P < 0.05, **P < 0.01. HEG, high hydrostatic pressure extract of ginseng; FAS, fatty acid synthase; HMGCR, 3-hydroxy-3-methyl-glutaryl CoA reductase
  • Figure 5. Effect of HEG on AMPK activity in HepG2 cells. Data are presented as mean ± SEM (n = 3) of experiments performed in triplicate. * P < 0.05, ** P < 0.01. HEG, high hydrostatic pressure extract of ginseng; AMPK, AMP-activated protein kinase