Figure 7. Proposed action pathway of TBE to regulate insulin IRS1/Akt signalling in insulin resistance mice. Under inflammatory conditions, TBE inhibited insulin tyrosine phosphorylation of IRS-1 via suppressed IKKβ phosphorylation, restoring transduction of the insulin IRS-1/Akt pathway

From

Tartary Buckwheat Extracts Regulate Insulin Sensitivity through IKKβ/IR/IRS-1/Akt Pathway under Inflammation Condition in Mice

Hanying Tian, Wenjun Zhao, Xudan Guo, Baolin Liu, Min Wang

Journal of Food and Nutrition Research. 2014, 2(6), 321-329 doi:10.12691/jfnr-2-6-9