Figure 3. Effect of Donepezil HCl on PC12 cells lesion induced by 10 μM Aβ25-35 Pretreatment of PC12 cells with 100 μM Donepezil HCl, prior to Aβ25-35 exposure, significantly decreased cell apoptosis, whereas the 1 μM and 5 μM Donepezil HCl slightly decreased Aβ25-35-induced cell apoptosis compared with Aβ25-35 alone. **p values < 0.01 when compared with the treatment of Aβ25-35 alone (n=6)

From

Study on Neuroprotective Capacity of Key Flavonoids of Ampelopsis grossedentata

Jiasheng Wang, Zhengwen Yu, Qiuping Yu, Qi Kong, Ni Zhang, Leilei He, Yin Yi

Journal of Food and Nutrition Research. 2014, 2(12), 880-889 doi:10.12691/jfnr-2-12-4