Figure 5. The modulation of apoptosis- related key biomarkers in A-549 cells treated with E-OHS (0, 0.1% DMSO, 50, or 100 μg/mL) for 12 h. The levels of pro-caspase-3 (A), pro-caspase-9 (B), caspase-12 (C), Bax (D), PARP, and cleaved-PARP (E) were analyzed using western blot analysis. Band densities were quantitated and displayed as bar graphs with GAPDH as an internal control. The results were obtained from three separate experiments and were expressed as the mean ± S.D. Statistical significance was determined as *p< 0.05; **p< 0.01; ***p< 0.001

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Anti-cancer Effect of the Ethyl Acetate Fraction from Opuntia humifusa on A-549 Human Lung Cancer Cells

Eon Ji Yeo, Myung Chul Cha, Dong Seok Lee

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