Table 3. Levels of total thiols (mmol/L), glutathione (GSH) (μg/mL), catalase (IU/L), superoxide dismutase (SOD) (U/mL), glutathione peroxidase (GSH-Px) (U/mL), and total antioxidant capacity (TAC) (nmol/mL), malondialdehyde (MDA) (nmol/mL), hydrogen peroxide (H2O2) (mmol/L), and total antioxidant capacity (TAC) (nmol/mL) in the tissue homogenates of different groups. The levels of total thiols, GSH, catalase, and TAC were significantly decreased in the tissue homogenates of cadmium-exposed rats compared to untreated control rats. MDA and H2O2 levels were significantly increased in the tissue homogenates of cadmium-exposed rats compared to untreated control rats. Rosmarinic acid-treated rats showed no significant differences compared to untreated control rats. The estimated biochemical parameters in tissue homogenates of rats exposed to cadmium and administered with rosmarinic acid demonstrated improvements toward the control levels and were significantly different compared to those measured in the cadmium-exposed rats

From

Rosmarinic Acid Supplementation Acts as an Effective Antioxidant for Restoring the Antioxidation/Oxidation Balance in Wistar Rats with Cadmium-Induced Toxicity

Mohammed Al-Zharani, Eman Almuqri, Mohammed Mubarak, Hassan Rudayni, Nada Aljarba, Khadijah Yaseen, Shaikha A. Albatli, Saad Alkahtani, Fahd A. Nasr, Amin A. Al-Doaiss, Mohammed S. Al-eissa

Journal of Food and Nutrition Research. 2024, 12(11), 528-536 doi:10.12691/jfnr-12-11-9