Figures index

From

Endothelium-Dependent Vasorelaxant Effect of a Bioactive Tripeptide, Valine-Proline-Proline, on Rat Aortic Rings

Jair Lozano-Cuenca, Oscar Alberto López-Canales, Ángel Miliar-García, María de los Ángeles Martínez–Godínez, Osiris Teran-Gallardo, María Cristina Paredes-Carbajal, Ruth Mery López-Mayorga, Enrique Fernando Castillo-Henkel, Héctor Flores-Herrera, Jorge Skiold López-Canales

Journal of Food and Nutrition Research. 2023, 11(8), 519-524 doi:10.12691/jfnr-11-8-1
  • Figure 1. Concentration-dependent relaxation of 10-9 - 10-4 M Val-Pro-Pro on endothelium-intact (closed circles) and endothelium-denuded (open circles) phenylephrine-precontracted rat aortic rings. Data are expressed as the mean ± SEM of n observations (n= 6). (*) P<0.001 vs (+) Endothelium.
  • Figure 2. Effects of 10-5 M L-NG-Nitroarginine Methyl Ester (L-NAME) (A) and 10-2 M tetraethylammonium (TEA) (B) on Val-Pro-Pro-induced vasorelaxation in functional endothelium rat aortic rings precontracted with 10-6 M phenylephrine (PE). Data are expressed as the mean ± SEM of n observations. (*) P<0.001 vs control.
  • Figure 3. Effects of: (A) 10-7 M apamin plus 10-7 M charybdotoxin, (B) 3.1 x 10-7 M glibenclamide and (C) 10-3 M 4-aminopyridine (4-AP) on Val-Pro-Pro-induced vasorelaxation in functional endothelium rat aortic rings precontracted with 10-6 M phenylephrine (PE). Data are expressed as the mean ± SEM of n observations (n=6). * P<0.001 vs control (two-way ANOVA).
  • Figure 4. Effects of 10-7 M ODQ (A) and 10-6 M KT 5823 (B) on Val-Pro-Pro-induced vasorelaxation in functional endothelium rat aortic rings precontracted with 10-6 M phenylephrine (PE). Data are expressed as the mean ± SEM of n observations. (*) P<0.001 vs control (two-way ANOVA).
  • Figure 5. Effects of 10-5 M Indomethacin (A) and 10-5 M cycloheximide (B) on Val-Pro-Pro-induced vasorelaxation in functional endothelium rat aortic rings precontracted with 10-6 M phenylephrine (PE). Data are expressed as the mean ± SEM of n observations.