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From
Isolation and Cloning of
sprA
Gene Alkaline Protease Activity from
Streptomyces flavogriseus
ADEM7 and Characterization of Its Antioxidant and Antitumor Activities
Doaa E. El-Hadedy, Nesreen A. Safwat, Abir Pertila, Rafat A. Siddiqui
Journal of Food and Nutrition Research
.
2023
, 11(5), 345-352 doi:10.12691/jfnr-11-5-2
Figure
1.
Restriction map and general specification of the cloning PGEM-T easy vector. The sequence of the multiple cloning sites is shown with a PCR product inserted by TAT cloning strategy
Full size figure and legend
Figure 2
.
The dose-response curve showing the in vitro inhibitory activity of the alkaline protease enzyme from the
Streptomyces flavogriseus
(exposed to gamma radiation or non-exposed) against human carcinoma cells after 48 h treatment using MTT assay. Where: (A) liver (HepG2) cell line, (B) breast (MCF-7) cell line, (C) colorectal intestinal (CACO2) cell line, (D) colon carcinoma (HCT-116) cell line. Results were shown as the mean viable cells % ± standard deviation of three independent experiments
Full size figure and legend
Figure 3.
DPPH radical scavenging activity of the alkaline protease enzyme from the
Streptomyces
flavogriseus (exposed to gamma radiation or non-exposed). Results were shown as the mean radical scavenging percentage ± standard deviation of three independent experiments
Full size figure and legend
Figure 4.
Diagrams illustrate Insertion SprA gene expressed extracellular protease alkaline fragment in PGEM vector by ligase enzyme
Full size figure and legend