Figure 1. Example of western blot showing the expression of BRCA2 (390 kDa) and BRCA1 (220 kDa) in breast cancer micro-biopsies cell lysates (n=54); as loading control β-actin is used. Most samples have lost BRCA1. Few samples have preserved BRCA2 while BRCA1 was lost (A1, H8 and I9). On this blot, two samples (A1 and I9) displayed isoforms of BRCA2. Number were scrambled to not trace patients.

From

BRCA1 Protein Deficiency in Breast Cancer Microbiopsy Lysate Delineates Patient Survival Time

Sara Hounguè, Terence Totah, Sophia George, Jean-Léon Olory-Togbé, Callinice D. Capo-chichi

Journal of Cancer Research and Treatment. 2021, 9(1), 1-11 doi:10.12691/jcrt-9-1-1