Figure 2. A photomicrograph of the cardiac sections from a) the control group showing normal morphology of the cardiac tissues (H&E ×250); b) DOX group showing inflammatory cellular infiltration among cardiac muscle cells (Mostly mature lymphocytes), swelling of the myocardial fibers with interstitial fibrosis (H&E ×400); c) DOX+I3C 1000 ppm group showing decreased inflammatory cellular infiltration among cardiac muscle cells with decreased swelling of the myocardial fibers (H&E ×400); d) DOX+I3C 2000 ppm group showing marked improvement in the inflammatory cellular infiltration and disorganization of myocardial fibers (H&E ×400)

From

Ameliorative Potential of Different Doses of Indol-3-carbinol on Doxorubicin-induced Cardiotoxicity in Mice

Almokhtar A. Adwas, Abeer A. Elkhoely, Ahmed M. Kabel, Mohamed Nabih Abdel-Rahman, Amany A. Eissa

Journal of Cancer Research and Treatment. 2016, 4(2), 26-31 doi:10.12691/jcrt-4-2-2