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From
Ameliorative Potential of Different Doses of Indol-3-carbinol on Doxorubicin-induced Cardiotoxicity in Mice
Almokhtar A. Adwas, Abeer A. Elkhoely, Ahmed M. Kabel, Mohamed Nabih Abdel-Rahman, Amany A. Eissa
Journal of Cancer Research and Treatment
.
2016
, 4(2), 26-31 doi:10.12691/jcrt-4-2-2
Figure 1
.
Effect of different treatments on the survival rate
Full size figure and legend
Figure 2
.
A photomicrograph of the cardiac sections from
a)
the control group showing normal morphology of the cardiac tissues (H&E ×250);
b)
DOX group showing inflammatory cellular infiltration among cardiac muscle cells (Mostly mature lymphocytes), swelling of the myocardial fibers with interstitial fibrosis (H&E ×400);
c)
DOX+I3C 1000 ppm group showing decreased inflammatory cellular infiltration among cardiac muscle cells with decreased swelling of the myocardial fibers (H&E ×400);
d)
DOX+I3C 2000 ppm group showing marked improvement in the inflammatory cellular infiltration and disorganization of myocardial fibers (H&E ×400)
Full size figure and legend