Figures 1A-1F. Photomicrographs of rat Liver sections in the different experimental groups stained with Haematoxylin & Eosin. A: Rat Liver sections in control group revealed normal structure of hepatocytes. B: Rat Liver section in GLE group revealed normal structure of hepatocytes (hp). C: Liver sections of MTX group showed moderate to severe lose of liver architecture, disturbance of the hepatocytes, congestion (Black arrows) in central veins (CV), atrophied, and vacuolated hepatocytes (White arrows). D&E: Liver sections in co-treated and post treated rat with GLE groups revealed a moderate to mild degree of improvement in hepatocytes where a few vacuolated hepatocytes (White arrows) and mild congestion in central veins were observed. F: Liver section in self treated showed severe lose of liver architecture, marked disturbance of the hepatocytes and strong marked hepatocellular vacuolation (White arrows)

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Abrogation by Ginkgo Byloba Leaf Extract on Hepatic and Renal Toxicity Induced by Methotrexate in Rats

Ehab Tousson, Zeinab Atteya, Afaf El-Atrash, Ola I. Jeweely

Journal of Cancer Research and Treatment. 2014, 2(3), 44-51 doi:10.12691/jcrt-2-3-1