Figure 3. Two HΦI groups at a distance of 25A (a), can be bridged by a water molecule. This is the same distance as the second nearest neighbors in ice (b)

From

Inversion of the Hydrophobic/Hydrophilic Paradigm Demystifies the Protein Folding and Self-Assembly of Problems

Arieh Ben-Naim

International Journal of Physics. 2013, 1(3), 66-71 doi:10.12691/ijp-1-3-2