Figures 2A-2F. Photomicrographs of rat kidney sections in the different groups under study stained with Haematoxylin & Eosin. A&B: Rat kidney sections in control and LC groups respectively showed normal structure of renal cortex which comprised renal corpuscles (White arrows), proximal and distal convoluted tubules. C: Rat kidney sections in MTX group showed glomerular damage (White arrows), vacuolization in tubular cells focal necrosis and cell infiltration (Black arrows). D: Kidney section of co-treated group with LC revealed a good degree of improvement glomerular damage with minimal vacuolization(Arrow heads) in tubular cells. E: Rat kidney section in post treated group with LC showed moderate organized tubular and glomerular structures except mild inflammatory infiltration (Black arrows). F: Kidney section of MTX self treated showed severe lose of kidney architecture, marked disturbance in glomeruli with strong inflammatory infiltration (Black arrows)

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Methotrexate-induced Hepatic and Renal Toxicity: Role of L-carnitine in Treatment

Ehab Tousson, Zaki Tawfeek Zaki, Walid Ali Abu-Shaeir, Hamada Hassan

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