Figure 8. Phase-contrast microscopy picture showing the proliferation and differentiation of mature neural cells from BM-MSCs after incubation in culture media supplemented with CSF:(a)Highly enriched area of differentiated mature bipolar neuronal cell (green arrow) and multipolar neuronal cell (red arrow) with multi-branched neurites contacting with mature oligodendrocyte (yellow arrow) after 5 days, white arrow indicate pro-oligodendrocyte contacting neuritis branches (Scale bar = 500µm). (b, b’) Enlargement of the red square area showing mature oligodendrocyte (yellow arrow) with granular cytoplasm which intensively produces myelin component and extending sheaths (yellow stars) contacting neurite branches (orange arrows) of the multipolar neuron (red arrow) for enveloping, black arrow showing cell body of unipolar neuron with coiled proximal axon (Scale bar = 100µm). (c)Mature multipolar neuronal cells after 5 days of culturing (Scale bar = 100µm). (d)Mature oligodendrocyte after 8 days, yellow arrows indicate dense granular cytoplasm area (rough endoplasmic reticulum during myelination), red arrow showing sheaths of membrane enveloping the contacting axon (white arrows) of the neighboring neuron (Scale bar = 100µm) : Transdifferentiation of Bone Marrow Mesenchymal Stem Cells into Neural Cells via Cerebrospinal Fluid : Science and Education Publishing