Figure 7. Photomicrographs showing the proliferation and differentiation of astroglial and mature astrocytes from BM-MSCs after incubation in culture media supplemented with CSF: (a)The white circle area in the phase-contrast microscopy picture showing neural stem cells with astroglial morphology describing a neurogenic niches of highly replicating cells (i.e. small neurogenic islands where neurons and glia are continuously generated) (Scale bar = 500µm). (b) Mature star-like structure astrocyte after 5 days (Scale bar = 100µm)

From

Transdifferentiation of Bone Marrow Mesenchymal Stem Cells into Neural Cells via Cerebrospinal Fluid

Dina Y. Otify, EmanA. Youssef, Naglaa B. Nagy, Mona K. Marei, Magda I. Youssif

Biomedicine and Biotechnology. 2014, 2(4), 66-79 doi:10.12691/bb-2-4-2