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From
Designing and Evaluation of Novel Valproic Acid Derivatives by IvLCB: In-vitro Like Computational Bioassay, Predictive Toxicological Study & Docking Analysis for GABA-A Mediated Inhibition of Neural Firing
Muskan Alvi, Vikash Pal, Sahil Kumar, Yash Kumar, Ajeet , Babita Kumar, Shabnam Ain, Qurratul Ain
American Journal of Pharmacological Sciences
.
2025
, 13(1), 19-32 doi:10.12691/ajps-13-1-3
Table 1. Descriptor of Lipinski rule of Five
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Table 2. Results found by IvLCB (in-vitro like computational bioassay)
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Table 3. Predictive Toxicological values for VAL1
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Table 4. Predictive Toxicological values for VAL2
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Table 5. Predictive Toxicological values for VAL3
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Table 6. Predictive Toxicological values for VAL4M
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Table 7. Predictive Toxicological values for VAL4O
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Table 8. Predictive Toxicological values for VAL4P
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Table 9. Predictive Toxicological values for VAL5M
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Table 10. Predictive Toxicological values for VAL5O
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Table 11. Predictive Toxicological values for VAL5P
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Table 12. Predictive Toxicological values for VAL6M
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Table 13. Predictive Toxicological values for VAL6O
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Table 14. Predictive Toxicological values for VAL6P
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Table 15. Predictive bioactivity score for the valproic acid derivatives
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Table 16. Predictive property for the Valproic acid derivatives
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Table 17. Docking results of all the compounds with receptor 4COF
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