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From
Salidroside Could Delays Aging by Regulating the Expression of TERT through Wnt/β-Catenin Pathway
Ke Cai, Xi Yu, Hongbo Li, Jie Zhai, Guanxi Wang
American Journal of Pharmacological Sciences
.
2025
, 13(1), 1-5 doi:10.12691/ajps-13-1-1
Fig
ure
1.
Salidroside improved learning and memory impairments of aging mice. (A) Representative searching strategy of mice on day 6 for the probe trial. (B) Left: escape latency to find the hidden platform in the test during the five consecutive days training. Right: the time of the mice spent in the quadrant where the platform was placed. *P < 0.05,
**
P <0.01 vs young group;
#
P < 0.05 vs old group
Full size figure and legend
Fig
ure
2
.
Effects of Salidroside on morphology in hippocampal CA1 in naturally aging mice (×400). Salidroside can improve the morphology of aging brain tissue in mice
Full size figure and legend
Fig
ure
3
.
Salidroside increased protein expression of TERT in hippocampus of aging mice via Wnt/β-catenin pathway. (A) The effect of salidroside on TERT protein expressions in hippocampus of aging mice. β-actin was considered as loading controls. (B) The original bands of Wnt, β-catenin and β-actin. The ratio of different proteins to β-actin was calculated by the band density.
*
P< 0.05 vs young group;
#
P< 0.05 vs old group
Full size figure and legend