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Pharmacokinetics of Indomethacin in Chronic Migraine Patients after Withdrawal from the Overused Combination of Indomethacin, Prochlorperazine and Caffeine
Anna Ferrari, Diego Pinetti, Daniela Gallesi, Alfio Bertolini, Grazia Sances, Emilio Sternieri
American Journal of Pharmacological Sciences
.
2013
, 1(5), 74-79 doi:10.12691/ajps-1-5-1
Table 1. Patients’ characteristics (mean+S.D.; range in brackets)
Full size table and legend
Table 2. Pharmacokinetic parameters (estimated by non-compartmental method) of indomethacin following rectal administration of IPC combination (indomethacin 50 mg, prochlorperazine 8 mg, caffeine 150 mg) in 9 chronic migraine patients before and after 3 months from in-patient withdrawal from the overused IPC combination (Group A: patients who relapsed into overuse; Group B: patients who steadily discontinued overuse)
Full size table and legend