Figure 2. Dose-dependent effect of AgNPs compared to AgNO₃ on inflammation and cytotoxic markers in BALF samples. Lungs were lavaged after 24 h of single intratracheal instillations of 25, 50 and 100 µg Ag/rat. (A) Neutrophils ratio (%), (B) LDH activity, (C) ALP activity, (D) βG activity, (E) IL-1β and (F) IL-18 concentrations. The results are shown as mean ± SD., n=4 for each group. (*) represented the significant difference from control group. (#) showed the significant difference from the corresponding AgNO₃-treated group

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Time-dependent Toxic Effect and Distribution of Silver Nanoparticles Compared to Silver Nitrate after Intratracheal Instillation in Rats

Alaa Fehaid, Mohamed F. Hamed, Mamdouh M. Abouelmagd, Akiyoshi Taniguchi

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