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From
Erythropoietic and Hepatoprotective Potential of Ethanolic Extract of
Nauclea
latifolia
in Mice Infected with
Plasmodium
berghei
berghei
Innocent A. Edagha, Inyang A. Atting, Rosemary B. Bassey, Enobong I. Bassey, Sediongde J. Ukpe
American Journal of Medical Sciences and Medicine
.
2014
, 2(1), 7-12 doi:10.12691/ajmsm-2-1-2
Group
1
.
A. Control – Liver X100 (H&E); B. Control – Liver X400 (H&E) (The micrographs show the Central vein (Cv), the plates of hepatic cells (Hc), Portal vein (Pv), Endothelial cells (Ec), Sinusoids (S). No abnormality seen)
Full size figure and legend
Group 2.
C. Pbb Only – Liver X100 (H&E); D. Pbb Only – Liver X400 (H&E). (The micrographs show the Central vein (Cv), the Portal vein (Pv), plates of hepatic cells (Hc), sinusoids (S), Hypertrophy, Inflammation, Numerous Karyorrhectic hepatic cells (Kc) and Necrosis (N). Strongly affected)
Full size figure and legend
Group 3.
E. Pbb + Coartem Liver X100(H &E), F. Pbb + Coartem Liver X400(H &E) (The micrographs show the Portal vein (Pv), Central vein (Cv), plates of hepatic cells (Hc), Sinusoids (S), sparse karyorrhectic cells (Kc) and Necrosis (N), few inflamed areas (If ). Strongly affected)
Full size figure and legend
Group 4.
G.
NL
500mg/kg Liver X100(H &E), H.
NL
500mg/kg Liver X400(H &E) (The micrographs show Central vein (Cv), plate of hepatic cells (Hc), Portal vein (Pv), few Pyknosis present. Slightly affected)
Full size figure and legend
Group 5.
I.
NL
1000mg/kg Liver X100 (H&E), J.
NL
1000mg/kg Liver X400 (H&E) (The micrographs show Portal vein (Pvs ), Bile duct (Bd), sparse clumping nuclei (Cn), numerous pyknosis (Py), numerous nuclei within lumen of Portal vein. Slightly affected)
Full size figure and legend
Group 6.
K. Pbb+NL 500mg/kg Liver X100 (H&E), L. Pbb+NL 500mg/kg Liver X400 (H&E) (The micrographs show Central Vein (Cv), Portal vein (Pv), Bile duct (Bd), plate of hepatic cells (Hc), widely interspersed clumping nuclei (Cn) and sparse pyknosis (Py). Strongly affected)
Full size figure and legend
Group 7.
M.
Pbb
+
NL
1000mg/kg Liver X100 (H&E), N.
Pbb
+
NL
1000mg/kg Liver X400(H&E) (The micrographs show numerous plates of hepatic cells (Hc), Portal vein (Pv), sparse pyknotic cell (Py), sparse clumping nuclei (Cn). Strongly affected)
Full size figure and legend