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From

Biological Activities of Brown Algae (Sargassum subrepandum) and Their Effects on Biochemical, Molecular and Histological Liver Damage Induced by Benzo[a]Pyrene in Rats

Yousif A. Elhassaneen, Amal N. Zaki, Basma G. Helmy, Asmaa I. Bayomi

American Journal of Medical Sciences and Medicine. 2024, 12(3), 64-79 doi:10.12691/ajmsm-12-3-2
  • Figure 1. Antioxidant activity of different brown algae extracts assayed by the BCB method. Each value represents the mean value of three replicates. BCB, β-carotene bleaching, BHT, Butylated hydroxytoluene, (α–tocopherol at 50 mg/L and BHT at 50 and 200 mg/L concentrations were used as references)
  • Figure 2. Dose-dependent inhibition of CuSO4-induced LDL oxidation in vitro by brown algae extracts. The conjugated diene formation was measured as the absorbance at 234 nm and the result is expressed as the area under the curve (AUC)
  • Figure 3. Dose-dependent ROO- scavenging capacity of Sargassum subrepandum as determined by improved oxygen radical absorbance capacity (ORAC) assay. EtOHE, ethanol extract, HE, hexan extract, AqE, water extract, and MeOHE, methanol extract
  • Figure 4. Electrophoretic pattern of nucleic acid in the tissue lysate of hepatic rats treated by feeding with brown algae (Sargassum subrependum) after being injected with B[a]P
  • Figure 5. Mean of maximal optical density of total RNA in tissue lysate of B[a]P injected rats liver feeding with brown algae (Sargassum subrependum) powder
  • Figure 6. Mean of maximum optical density of apoptotic fragments of DNA in hepatic rats treated by feeding with brown algae (Sargassum subrependum) after being injected with B[a]P.
  • Figure 7. Mean of maximum optical density of apoptotic fragments of DNA in hepatic rats treated by feeding with brown algae (Sargassum subrependum) after being injected with B[a]P
  • Figure 8. Effect of intervention with Sargassum subrepandum ethanol extract (SSEE) on B[a]P-induced liver histopathological alterations in rats liver tissue (H & E X 400, scale bar 50μm)