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From

To Estimate Pulmonary Arterial Compliance and Pulse Wave Velocity in Cerebral-Cardiovascular Patients Using CT Cardiac Images

WeiChih Hu, Hsuan-Ming Tsao, Jian Xiang Zhi, Harmon Chris T. Herman, Lemmuel L. Tayo, Yashbir Singh, Kathiravan S, João Manuel R.S. Tavares, Chandan Chakraborty

American Journal of Medical and Biological Research. 2017, 5(2), 23-30 doi:10.12691/ajmbr-5-2-3
  • Figure 1. Developed computational pipeline for the determination of ROI volumes in CT images
  • Figure 2. One electrocardiogram partitioned into ten time series.
  • Figure 3. Seeded region growing algorithm used in the first segmentation step
  • Figure 4. The central axis position is determined, in this representative slice, as the intersection of all normal lines perpendicular to the tangent points
  • Figure 5. The result of (A) regression analysis of the comparison between RV and LV stroke volumes as assessed by CT imaging, and (B) Bland-Altman analysis for the evaluation of the agreement between RVSV and LVSV measurements. The average of RV and LV SV for each patient (x-axis) and the difference between RV and LV SV for each patient studied (y-axis)
  • Figure 6. The result of seeded region growing algorithm is showing endocardial boundary of (A) The left ventricle and (B) The right ventricle with over segmentations
  • Figure 7. The result of the snake algorithm is showing endocardial boundary of (A) left ventricle and (B) right ventricle without over segmentation
  • Figure 8. Segmentation of PA: (A) SRG segmentation result of the whole pulmonary artery, (B) 3D reconstruction and main PA determination, and (C) reconstructed 3D model were shown mainly using in PA volume extraction.
  • Figure 9. 3D resampled image of the heart is showing (A) the main pulmonary in red and right ventricle in blue and (B) the left ventricle in red and right ventricle in blue
  • Figure 10. Result of the regression analysis of the comparison between (A) pulmonary arterial compliance and pulse wave velocity, and (B) between right ventricular compliance and pulse wave velocity
  • Figure 11. Right ventricular compliance and pulmonary compliance of patients with (A) AF and SR and (B) SR into AF
  • Figure 12. Pulse wave propagation (PWP) plot for our nine patients are showing the time series (x-axis) vs the pixel intensity (y-axis)
  • Figure 13. Intra- and inter-observer Bland-Altman analyses for pulmonary arterial compliance. Mean (95% limits of agreement) intra- and inter-observer differences were 0.008 ml/mmHg (-0.0124-0.0276 ml/mmHg) and 0.008 ml/mmHg (-0.0206-0.03658 ml/mmHg), respectively
  • Figure 14. Intra- and inter-observer Bland-Altman analyses for pulse wave velocity. Mean (95% limits of agreement) intra- and inter-observer differences were 0.006 m/s (-0.0228-0.0347 m/s) and -0.0115 m/s (-0.0536-0.0305 m/s) for PWV, respectively