This special issue report a series of new clinical treatment data for improve patients with lymphoma and some cases about common hematologic malignancies in west of Iran. Dr. Mehrdad Payandeh (MD) and other his colleagues as scientific groups gathered and provide these reports in field of Hematologic malignancy. This issue show common cases that they can be different in comparison with other part of the world cancer therapy cause availability of the drugs and cost of them. We must to try for increased level of treatment policy in our area.