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From
The Prediagnosis of Prostate Cancer Risk is Possible with the Evaluation of BRCA1 Primary Exons in Men
Haboubacar Elhadji Yaou Moussa, Maazou Halidou, Sara Y. Houngue, Josué Avakoudjo, Solomon Oladapo Rotimi, Callinice D. Capo-Chichi
American Journal of Cancer Prevention
.
2023
, 10(1), 14-20 doi:10.12691/ajcp-10-1-4
Figure 1
.
Histogram summarizing the survey data. The distribution of prostate cancer by age group shows that majority of patients are above 71 years followed by 51 to 70 years. Younger than 50 years patients were among the study population
Full size figure and legend
Figure 2
.
Histogram showing total PSA level distribution from low to high value among prostate cancer patients.
Normal PSA is lower than
4 ng/ml, suspect PSA is between 4 - 10 ng/ml while prostate cancer related PSA is abnormally higher than 10 ng/ml
Full size figure and legend
Figure 3
.
Agarose gel showing the amplification of exons 1 (above) and exons 2 (bottom) of the BRCA1 gene by PCR.
Absence of band is indicator of mutation on the targeted exon
. T: Witness, B: Benin, N: Niger
Full size figure and legend
Figure 4
.
Gel showing the PCR product of BRCA1 exons 3 (above) and exons 5 (bottom). Sample B2 and N5 are missing exon 3 and exon 5 while samples N4 and N5 are missing exon 5 but not exon 3
Full size figure and legend
Figure 5
.
Percentage of absence of exons 1, 2, 3 and 5 in our study population. Globally for Benin (B) and Niger (N) together [36] the loss was 17.53 % for exon 1 (Ex1); 31.34% for exon 2 (Ex2); 19.5% for exon 3 (Ex3) and 31.63 % for exon 5 (Ex5). Nos mutations was observed the control samples (Temoins)
Full size figure and legend