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From

Analyses of IL-6, IL-10, IL-17A, INF-γ and TNF-α Cytokines in Diseases of Mucopolysaccharidosis Type I and Mucopolysaccharidoses Type VI

B.J. Vieira, A.S. Blembeel, G.P. Dorneles, J. Cé, A. Peres, J.C. Coelho, A.S. Mello

American Journal of Biomedical Research. 2019, 7(1), 3-8 doi:10.12691/ajbr-7-1-2
  • Figure 1. Inflammatory mediators: IL6, TNFα, IFN, IL17 and IL10. Immunohistochemical staining in the serum (pg/mL) of Mucopolysaccharidose Type I (MPSI) and Control samples (Controls). Data are expressed in mean ± SD. Statistical p values were obtained with the Student's t-test. * Statistical differences according to Levene's test (p < 0.05)
  • Figure 2. Inflammatory mediators: IL6, TNFα, IFN, IL17 and IL10. Immunohistochemical staining in the serum (pg/mL) of Mucopolysaccharidose Type VI (MPSVI) and Control samples (Controls). Data are expressed in mean ± SD. Statistical p values were obtained with the Student's t-test. * Statistical differences according to Levene's test (p < 0.05)
  • Figure 3. Serum correlation between MPSVI patients and Control samples: IL-6 e IL-17A (r= -0,786; p= 0,036). Correlations between variables were performed through Spearman Test
  • Figure 4. ROC curves evaluated the specificity and sensitivity of the determination of TNFα in the discrimination between MPS I (A) and MPS VI (B).