Plate III. Section of the liver of a rat treated with methanol seed extract (300 mg/kg) for 21 days. Note the congestion (arrow heads) and severe diffuse necrosis of the hepatocytes (G). H and E stain. x400

From

Hepatotoxicity of Methanol Seed Extract of Aframomum melegueta [Roscoe] K. Schum. (Grains of paradise) in Sprague-Dawley Rats

Nwaehujor Chinaka O., Eban Linus K., Ode Julius O., Ejiofor Charles E., Igile Godwin O.

American Journal of Biomedical Research. 2014, 2(4), 61-66 doi:10.12691/ajbr-2-4-1