Figure 4. Serum insulin levels (µIU/ml) and HOMA-IR values of different studied groups at the end of the treatment period (4 weeks). Values are presented as mean ± SE (n = 10). The abbreviations denote Glim: rats treated with glimepiride (0.1 mg/kg), Sita 10: rats treated with sitagliptin (10 mg/kg) and Sita 30: rats treated with sitagliptin (30 mg/kg). a: significantly different from the control group, b: significantly different from the diabetic untreated group, c: significantly different from the Glim group, d: significantly different from the Sita 10 group, using ANOVA (LSD), p value < 0.05

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Effect of Sitagliptin and Glimepiride on Glucose Homeostasis and cAMP Levels in Peripheral Tissues of HFD/STZ Diabetic Rats

Mohamed I Saad, Maher A Kamel, Mervat Y Hanafi, Madiha H Helmy, Rowaida R Shehata

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