Figure 1. Correlation between plasma ratios of DHA/AA (Figure 1a) and EPA/AA (Figure 1b) and the ABC five subscale and total scores. Solid lines indicated Spearman’s rank correlation coefficients in the 30 individuals with ASD and dotted lines indicated the 20 normal controls. Plasma DHA/AA and EPA/AA ratios were significantly correlated with all five ABC subscale scores and total scores (all r values were greater than 0.32, p < 0.05, p < 0.01 or p < 0.001) (Spearman’s rank correlation coefficients)


Down-regulation of Signaling Mediator in Related to Increased Ratio of Docosahexaenoic Acid/Arachidonic Acid in Individuals with Autism Spectrum Disorders

Kunio Yui, George Imataka, Yohei Kawasaki, Tsutomu Yamada

Journal of Translational Medicine and Developmental Disorders. 2015, 2(1), 1-9