Figure 2. Plant extracts decreased nuclear and mitochondrial DNA lesions in UVB-irradiated keratinocytes. HNKC were first pre-treated during 3h with AA, PI, PR or MIX (values shown as µg/mL) before irradiation with UVB (60mJ cm-2). AP sites lesions of nuclear (upper panel) and mtDNA (lower panel) were quantified 24h later and results are shown as the percentage of lesions, compared to untreated UVB-irradiated cells (black column). p values compared data from treated to untreated irradiated HNKC. Data show mean from 3 ± SD from distinct HNKC preparations


Sublethal UVB Induces DNA Lesions and Pro-Apoptotic Gene Transcription in Human Keratinocytes: Attenuation by a Mixture of Plant Extracts

Rachid Ennamany, Nadine Leconte, Jacques Lecrlerc, Aliza Jabès, Hamid-Reza Rezvani, Jérôme Rambert, Khaled Ezzedine, M. Djavad Mossalayi

World Journal of Preventive Medicine. 2013, 1(2), 4-10 doi:10.12691/jpm-1-2-1