Figure 5. The effect of FJH-BS on the mRNA expression of IL-1β (A), IL-6 (B), TNF-α (C), aggrecan (D), collagen type I (E), collagen type II (F), TIMP-1 (G), TIMP-2 (H), TIMP-3 (I), MMP-3 (J), MMP-7 (K), and MMP-13 (L) in the articular cartilage from rats with MIA-induced osteoarthritis using RT-PCR. Normal Control: AIN93G diet; Control: AIN93G diet + MIA injected group; MSM (positive control): AIN93G diet + MIA injected group supplemented with MSM 150 mg/kg b.w.; FJH-BS Low: AIN93G + MIA injected group supplemented with FJH-BS 80 mg/kg b.w.; and FJH-BS High: AIN93G + MIA injected group supplemented with FJH-BS 125 mg/kg b.w. Values are presented as mean + SD (n=8). Different letters (a > b > c > d > e) indicate a significant difference with p < 0.05, as determined using the Duncan’s multiple range test

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Standardized Ethanolic Extracts of Boswellia serrata Ameliorate Symptoms of Osteoarthritis by Direct Effects on Chondrocytes

Jihee Lee, Inae Jeong, Gwang-Woo Kim, Taesang Son, Yujeong Kim, Woojin Jun, Jeongjin Park, Ok-Kyung Kim

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