Figure 5. Micrography of hypothalamic coronal sections showing the Arcuate Nucleus (10X) of mice fed with A) Standard Diet (SD), B) Standard Diet with Cactus Flour (SD-CF) , C) High Fat Diet (HFD) and D) High Fat Diet with Cactus Flour (HFD-CF). 3V is the third ventricle. E) Total microglial density (cell number/mm2) in the arcuate nucleus and F) Activated microglial density (cell number/mm2) in the arcuate Nucleus of SD, SD-CF, HFD and HFD-CF groups. Data were analyzed with one-way ANOVA followed by Bonferroni’s post hoc test, shown in means ± SEM n=7, *P≤0.05 vs SD


Addition of Opuntia ficus-indica Reduces Hypothalamic Microglial Activation and Improves Metabolic Alterations in Obese Mice Exposed to a High-fat Diet

Mercedes Victoria Urquiza-Martínez, Héctor Eduardo Martínez-Flores, Omar Guzmán-Quevedo, Ana Elisa Toscano, Raul Manhães de Castro, Luz Torner, Rosalío Mercado-Camargo, Rosa Elena Pérez-Sánchez, María Carmen Bartolome-Camacho

Journal of Food and Nutrition Research. 2020, 8(9), 473-483 doi:10.12691/jfnr-8-9-4