Figure 3. Effects of aqueous (A) and ethanolic extracts (B) of decaffeinated coffee on carrageenan-induced hypernociception in mice measured using the electronic pressure meter. The animals were pretreated orally with vehicle, AD or ED (30, 100 and 300 mg/kg) or morphine (10 mg/kg) prior to intraplantar injections of carrageenan. The results indicate the mean ± S.E.M for six mice in each group. The asterisks indicate the following significance level when compared to the control group: ***p < 0.001 (Newman-Keuls).

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Anti-inflammatory and Antinociceptive Activities of Decaffeinated Coffee

Maria Eliza de Castro Moreira, Rosemary Gualberto Fonseca Alvarenga Pereira, Daniele Ferreira Dias, Claudinei Alves da Silva, Thiago Corrêa de Souza, Éderson D’Martin Costa, Bárbara Pereira da Silva, Stella Maris da Silveira Duarte, Alexandre Giusti-Paiva, Marcelo Henrique dos Santos

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