Figure 2. Lipid deposition and indicators of liver function of rats fed either a control or high-fat diet with addition of araçá or not. Representative hematoxylin and eosin-stained histological sections of livers from rats fed a control or high-fat diet treated with araçá (A). Normal hepatocytes in C and CAF groups. Presence of macro (white arrow) and microvesicular (black arrow) steatosis in HF and HFAF groups. C: Control. CAF: Control + Araçá. HF: High-fat. HFAF: High-fat + Aracá. Images photographed at 400× magnification. Relative liver weight (B), degree of liver steatosis (C) and activity of the enzymes ALT and AST (D). Data in (B and D) are represented as mean ± standard deviation. (*) Indicates significant difference of diet, (#) indicates significant difference of araçá and different letters indicate interaction between diet and araçá, by two-way ANOVA test followed Tukey’s post-test. Data in (C) are represented as median and interquatile range. Different letters indicate interaction between diet and araçá, by Kruskal-Wallis test followed by Dunn’s post-test. Significant differences were considered for p < 0.05


Araçá (Psidium cattleianum Sabine) Ameliorates Liver Damage and Reduces Hepatic Steatosis in Rats Fed with a High-fat Diet

Alice Helena S. PAULINO, Ana Maria F. VIANA, Larissa F. BONOMO, Joyce Ferreira C. GUERRA, Juliana Márcia M. LOPES, Ana Carolina S. RABELO, Miliane Martins A. FAGUNDES, Ana Lúcia Rissoni S. RÉGIS, Wanderson G. LIMA, Maria Lúcia PEDROSA, Marcelo Eustáquio SILVA

Journal of Food and Nutrition Research. 2019, 7(2), 132-140 doi:10.12691/jfnr-7-2-5