Figure 3. Effect of quercetin on IRE1α, XBP-1, and GRP78 expression in TNF-α-induced HepG2 cells. (A) Representative Western blots for total protein and phosphorylation of IRE1α in TNF-α-induced HepG2 cells. (B) mRNA expression of XBP-1 in TNF-α-induced HepG2 cell. (C) mRNA expression of GRP78 in TNF-α-induced HepG2 cell. The data are expressed as the mean ± standard deviation (n=3). The different letters show a significant difference at p < 0.05 as determined by Duncan’s multiple range test


Defensive Effect of Quercetin against Tumor Necrosis Factor α-induced Endoplasmic Reticulum Stress and Hepatic Insulin Resistance in HepG2 Cells

Jeongjin Park, Woojin Jun, Jeongmin Lee, Ok-Kyung Kim

Journal of Food and Nutrition Research. 2018, 6(8), 518-524 doi:10.12691/jfnr-6-8-6