Figure7. IκBphosphorylation and NF-κB activation in LPS-induced Caco-2 and HT-29 cells by treated with curcumin. The expression level of phosphorylated IκB (pIκB), IκB, and cytosolic/nuclear NF-κB proteins were detected by Western blot. Actin expression was as the loading control. The bar chart presented the relative quantification of p-IκB expression normalized by IκB protein expression The data was repeated 3 times independently to ensure reproducibility and the standard deviation of the mean are represented as error bars (n=3). Values with different letters were significantly different (p< 0.05) at corresponding concentrations between different treatments

From

Curcumin Suppresses the Activity of Inhibitor-κB Kinase in an in vitro Inflamed Human Intestinal Mucosa Model by S-nitrosylation

Ning-Jo Kao, Zwe-Ling Kong

Journal of Food and Nutrition Research. 2017, 5(6), 406-412 doi:10.12691/jfnr-5-6-7