Figure 1. The effect of brazilin on NF-κB luciferase activity in LPS-stimulated Raw264.7 cells. (A) The chemical structure of brazilin. (B) NF-κB luciferase activity of brazilin. Cells were incubated with increasing concentration of the brazilein for 1h and then co-treated with 1 μg/mL LPS for 10 h. DMSO was used as a vehicle. Data are mean ± SD (n=3)

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Brazilin Suppresses Inflammation via the Down-regulation of IRAK4 in LPS-stimulated Raw264.7 Macrophage

Kye-Yoon Yoon, Kui-Jin Kim, Hyung-Sun Youn, Sei-Ryang Oh, Boo-Yong Lee

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