Studies indicate that omega-3 fatty acids have positive effects on reducing heart diseases several such as myocardial infarction, cardiac arrhythmia, atherosclerosis thrombosis and hypertension. The omega-3 PUFA EPA and DHA are important throughout life and are a dietary necessity found predominantly in fish and fish-oil supplements. In this research, the liver and muscle tissues of Scomberomorus commerson from the Iranian Port of Bandar Abbas in March 2015 were separately extracted for their lipid content especially omega-3 fatty acids composition using the method of Blight & Dyer. The compounds were determined by Gas Chromatography-Mass Spectrometry (GC- MS). The components detected in the liver and muscle tissues, were Palmitic acid, Oleic acid, Eicosapentaenoic acid (EPA) and Docosahexaenoic acid (DHA). The result of this study show that the muscle and liver tissues of Scomberomorus commerson are rich sources of omega-3 fatty acids EPA (18.12-21.63%) and DHA (17.37-19.12- %).
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